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The appropriate dose of boneset depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for boneset. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.Boneset is an immune stimulant and diaphoretic that helps fight off minor viral infections, such as the common cold. Several double-blind trials have found that echinacea root tinctures in combination with boneset, wild indigo , and homeopathic arnica reduce symptoms of the common cold. In addition, linden and hyssop may promote a healthy fever and the immune system's ability to fight infections . Yarrow is another diaphoretic that has been used for relief of sore throats, though it has not yet been researched for this purpose.
A small number of people experience nausea and/or vomiting when using boneset. The fresh plant, however, is more likely to cause this than the dried herb. Although potentially liver-damaging chemicals, called pyrrolizidine alkaloids, are found in some plants similar to boneset, the levels in boneset are minimal. There are no known reports of liver damage from taking boneset. Nevertheless, patients with liver disease should avoid boneset, and no one should take it consistently for longer than six months. Boneset is not recommended during pregnancy or breast-feeding. Boneset should not be used when a high fever (over 102 degrees F) is present.In Heal Local: 20 Essential Herbs for Do-It-Yourself Home Healthcare(New Society Publishers, 2015) author and herbalist Dawn Combs makes herbal healthcare less intimidating and more attainable, helping locally-minded gardeners and non-gardeners alike take back food, goods and services from pharmaceutical corporations and sourcing them from small growers, producers, artisans and entrepreneurs. This section on Boneset comes from the chapter “The Herbs.”
There is some argument about whether or not this herb is useful for broken bones, but I am convinced that it is. It can be used to recalcify teeth, ease bone pain and repair crushed and broken bones. It seems to do that by increasing the blood flow to the periosteum, the thin tissue surrounding our bones. It is also helpful for osteoporosis and osteomalacia. Complimentarily it seems that boneset also works on the joints and nerves that are part of the skeletal system. It can be used for multiple sclerosis and it has been shown to rebuild the myelin sheath. Boneset (Eupatorium Perfoliatum) also known as thoroughwort, sweat plant, vegetable antimony , feverwort , agueweed , Indian sage , sweating plant , eupatorium , crosswort , thoroughstem , thoroughwax , wild Isaac, Wood boneset, teasel, tearal and wild sage is a flowering plant in the Asteraceae, or daisy, family which also includes asters and daisies. The plant is native to Eastern United States and Canada, extending north to Nova Scotia and south to Florida, and can be found eastward in Manitoba and Texas. This was introduced to the American colonists by Indians who had been using this for breaking fever with the help of heavy perspiration. It is found near low wet patches and near Reed Canary grass. The common name, boneset, comes from breakbone fever, an influenza-like illness causing severe bone pain that was treated with Eupatorium perfoliatum. The herb was used as a charm. The root fibers are applied to hunting whistles because of the belief that it would increase the whistle’s ability to call deer. Indians also used the plant as an anti-pyretic. It was also used to relieve rheumatism, influenza, dropsy and dengue. (Source: www.healthbenefitstimes.com)