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What Is a Geranium OOR

What Is a Geranium OOR

What Is a Geranium OOR

Burdette, J. E., Chen, S. N., Lu, Z. Z., Xu, H., White, B. E., Fabricant, D. S., Liu, J., Fong, H. H., Farnsworth, N. R., Constantinou, A. I., van Breemen, R. B., Pezzuto, J. M., and Bolton, J. L. Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. J Agric.Food Chem 11-20-2002;50(24):7022-7028. View abstract.

Geranium

Sammartino, A., Tommaselli, G. A., Gargano, V., di, Carlo C., Attianese, W., and Nappi, C. Short-term effects of a combination of isoflavones, lignans and Cimicifuga racemosa on climacteric-related symptoms in postmenopausal women: a double-blind, randomized, placebo-controlled trial. Gynecol.Endocrinol. 2006;22(11):646-650. View abstract. Since the publication of the results of the Women's Health Initiative that described the risks of hormone replacement therapy, many women are actively seeking alternative treatments for menopausal symptoms. Black cohosh (Actaea racemosa, syn. Cimicifuga racemosa) is one such alternative that has been used in the US for over 100 years.

To date only two cimicifuga extracts have been tested clinically, and the current recommended dosage is 40-80 mg/day. Review of the published clinical data suggests that cimicifuga may be useful for the treatment of menopausal symptoms, such as hot flashes, profuse sweating, insomnia, and anxiety. However, the methodology used in most of the trials is poor and further clinical assessment of cimicifuga is needed. In terms of safety, transient adverse events such as nausea, vomiting, headaches, dizziness, mastalgia, and weight gain have been observed in clinical trials. A few cases of hepatotoxicity have been reported, but a direct association with the ingestion of cimicifuga has not been demonstrated. The most recent data suggest that cimicifuga is not estrogenic. Efficacy of black cohosh (Cimicifuga racemosa) medicines for treatment of menopausal symptoms - comments on major statements of the Cochrane Collaboration report 2012 "black cohosh (Cimicifuga spp.) for menopausal symptoms (review)". (Source: pubmed.ncbi.nlm.nih.gov)

 

 

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